The effect of topical applications containing Benzalkonium chloride (BAK) and the relationship with Ocular Surface Disease is well established, even in concentrations as low as 0.005%1
Patients with Dry Eye Disease (DED), particularly those who require frequent use of lubricants or other topical therapies, should avoid ocular lubricants that contain Benzalkonium chloride (BAK).2
NICE guidelines3 recommend the following for moderate to severe Dry Eye patients:
“Consider preservative-free formulations if; the person is intolerant of preservative in tear supplements; has moderate to severe dry eye disease requiring drops more than 4 times per day; is using multiple preserved topical medications; or uses soft or hybrid contact lens.”
Professor Harminder Dua, one of the world’s leading authorities on the cornea and ocular surface disease explains some of the issues in the videos below.
Thea have been pioneers in ophthalmology for 150 years, specialising in preservative-free formulations and innovative delivery systems. We are committed to making preservative-free products accessible and cost-effective for patients and the NHS and aim to invest in educational programmes to benefit both healthcare professionals and patients.
Théa invented the first multi-dose bottle capable of dispensing preservative-free eye drops: the ABAK® bottle. The ABAK® bottle is a high-security, high-technology dispenser which delivers up to 300 drops through a filter which prevents microbial contamination. Continual innovations have made it smaller, more user-friendly and more effective. The contents can now be used for up to 3 months after opening as opposed to between 2 and 4 weeks for a classical preserved multi-dose bottle. Protected by patents, the design has been specifically created so that patients with weaker hand strength can instill drops; — it requires only 1⁄3 of the strength needed by other bottles.4